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CCR-2 Recombinant Rabbit mAb (bsm-62473R)  
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25ul/800.00元
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產(chǎn)品編號(hào) bsm-62473R
英文名稱 CCR-2 Recombinant Rabbit mAb
中文名稱 細(xì)胞表面趨化因子受體2重組兔單抗
別    名 C-C chemokine receptor type 2; C-C CKR-2; CC chemokine receptor type 2; CC CKR 2; CC-CKR-2; CCCKR2; CCR 2; CCR-2; ; CCR1L; ; CCR2.  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號(hào)
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:1000-1:2000,IHC-P=1:100-1:500,IHC-F=1:100-1:500,IF=1:100-1:500,Flow-Cyt=1:20-1:100,IP=1:20-1:50
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42 kDa
檢測分子量 42
性    狀 Liquid
免 疫 原 A synthesized peptide derived from human CCR2: 45683 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
保存條件 Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 Receptor for the MCP-1, MCP-3 and MCP-4 chemokines. Transduces a signal by increasing the intracellular calcium ions level. Alternative coreceptor with CD4 for HIV-1 infection.

SWISS:
P41597

Gene ID:
729230

CCR-2是屬于G蛋白偶聯(lián)受體一家族,參與調(diào)節(jié)白細(xì)胞的遷移和活性作用,是細(xì)胞膜蛋白,它的變異與HIV-1抵抗有關(guān)。CCR-2不僅在宮頸癌組織中表達(dá),而且在人其他腫瘤如白血病、淋巴瘤、乳腺癌、腎B 癌、胃癌、結(jié)腸癌、肝癌和子宮癌中均有過度表達(dá),可作為肝癌及乳腺癌診斷的標(biāo)志物。
產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded Human Breast Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CCR-2 Monoclonal Antibody, Unconjugated(bsm-62473R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Esophagus Cancer; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CCR-2 Monoclonal Antibody, Unconjugated(bsm-62473R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Esophagus; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CCR-2 Monoclonal Antibody, Unconjugated(bsm-62473R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Spleen; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CCR-2 Monoclonal Antibody, Unconjugated(bsm-62473R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Lymph; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CCR-2 Monoclonal Antibody, Unconjugated(bsm-62473R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Lung; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CCR-2 Monoclonal Antibody, Unconjugated(bsm-62473R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
Paraformaldehyde-fixed, paraffin embedded Human Tonsil; Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15 min; Antibody incubation with CCR-2 Monoclonal Antibody, Unconjugated(bsm-62473R) at 1:200 overnight at 4°C, followed by conjugation to the bs-0295G-HRP and DAB (C-0010) staining.
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