產(chǎn)品編號 | bsm-62709R |
英文名稱 | UFD1L Recombinant Rabbit mAb |
中文名稱 | 泛素融合降解樣蛋白1重組兔單抗 |
別 名 | UB fusion protein 1; UFD1; UFD1L. |
抗體來源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號 | |
交叉反應(yīng) | Human,Mouse,Rat |
產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 35 kDa |
檢測分子量 | 35,40 |
性 狀 | Liquid |
免 疫 原 | A synthesized peptide derived from human UFD1: 26-51 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Essential component of the ubiquitin-dependent proteolytic pathway which degrades ubiquitin fusion proteins. The ternary complex containing UFD1, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope. SWISS: Q92890 Gene ID: 7353 |
產(chǎn)品圖片 | |