產(chǎn)品編號(hào) | bsm-62786R |
英文名稱 | HTRA1 Recombinant Rabbit mAb |
中文名稱 | 絲氨酸蛋白酶11重組兔單抗 |
別 名 | ARMD7; CARASIL; High-temperature requirement A serine peptidase 1; HtrA; HtrA serine peptidase 1; HTRA1; IGFBP5 protease; ORF480; Protease serine 11(IGF binding); protease serine 11; PRSS11; Serine protease 11; Serine protease HTRA1. |
抗體來源 | Rabbit |
克隆類型 | Recombinant |
克 隆 號(hào) | |
交叉反應(yīng) | Human |
產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
理論分子量 | 51 kDa |
檢測分子量 | 51 |
性 狀 | Liquid |
免 疫 原 | A synthesized peptide derived from human Serine protease HTRA1: 350-400 |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
PubMed | PubMed |
產(chǎn)品介紹 |
Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. SWISS: Q92743 Gene ID: 5654 |
產(chǎn)品圖片 | |