| 產(chǎn)品編號(hào) | bs-3807R |
| 英文名稱 | PLAA Rabbit pAb |
| 中文名稱 | 磷脂酶A2激活蛋白抗體 |
| 別 名 | PLAP_HUMAN; phospholipase A-2-activating protein; PLAP; PLA2P; phospholipase A2 activating protein; DOA1; NDMSBA; |
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Specific References (1) | bs-3807R has been referenced in 1 publications.
[IF=3.71] Rosing, Katharina, et al. Everolimus therapy is associated with reduced lipoprotein-associated phospholipase A2 (Lp-Pla2) activity and oxidative stress in heart transplant recipients. Atherosclerosis. 2013 Sep;230(1):164-70. WB ; Human, Mouse.
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| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 激酶和磷酸酶 |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Cow,Dog,Horse) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 87 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human Phospholipase A2 activator protein: 101-200/795 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Phospholipase A2 activator protein (PLAP), activates PLA2 (phospholipase A2 enzyme) and is an important mediator of eicosanoid generation. Also known as a pro-inflammatory agent, PLAP has been found in inflamed tissues and synovial fluid from patients with rheumatoid arthritis. As such, it is believed to play an important role in the regulation of inflammatory diseases. The formation of PLAP can be stimulated by IL-1 beta and TNF-alpha. SWISS: Q9Y263 Gene ID: 9373 Database links: Entrez Gene: 9373 Human Omim: 603873 Human SwissProt: Q9Y263 Human Unigene: 27182 Human 磷脂酶A2激活蛋白能激活磷脂酶A2，是類(lèi)花生酸形成的一個(gè)重要中介體。作為促炎癥反應(yīng)劑，PLAP存在于類(lèi)風(fēng)濕性關(guān)節(jié)炎患者的炎癥組織和滑膜液，因而被認(rèn)為在炎癥性疾病調(diào)控中發(fā)揮重要作用。IL-1β和TNF-α能刺激PLAP的形成。PLAP作為睪丸精原細(xì)胞瘤的標(biāo)志物。 |
