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ABCA5 Rabbit pAb (bs-7940R)  
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50ul/1180.00元
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產品編號 bs-7940R
英文名稱 ABCA5 Rabbit pAb
中文名稱 三磷酸腺苷結合盒轉運蛋白A亞基5抗體
別    名 ABC13; ATP binding cassette sub family A(ABC1) member 5; ATP binding cassette A5; ATP binding cassette sub family A member 5; DKFZp451F117; DKFZp779N2435; EST90625; FLJ16381; KIAA1888; ABCA5_HUMAN.  
研究領域 細胞生物  細胞周期蛋白  轉錄調節(jié)因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human,Mouse,Rat,Sheep)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ELISA=1:5000-10000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 186 kDa
檢測分子量
細胞定位 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ABCA5: 1401-1500/1642 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 ABCA5 is a member of the superfamily of ATP binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ABCA5 is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. ABCA5 is localized in the lysosome, late endosome and Golgi apparatus membrane and is thought to play a role in the processing of autolysosomes.

Function:
May play a role in the processing of autolysosomes (By similarity).

Subcellular Location:
Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein (By similarity).

Tissue Specificity:
Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta.

Post-translational modifications:
N-glycosylated (By similarity).

Similarity:
Belongs to the ABC transporter superfamily. ABCA family.
Contains 2 ABC transporter domains.

Gene ID:
23461

Database links:
UniProtKB/Swiss-Prot: Q8WWZ7.2

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