| 產(chǎn)品編號(hào) | bs-9149R |
| 英文名稱 | TRIM35 Rabbit pAb |
| 中文名稱 | TRIM35蛋白抗體 |
| 別 名 | Hemopoietic lineage switch protein 5; HLS5; KIAA1098; Macrophage derived apoptosis inducing RBCC protein; MAIR; NC8; Protein MAIR; Protein Nc8; Tripartite motif containing 35; Tripartite motif containing protein 35; TRI35_HUMAN. |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Rabbit,Pig,Sheep,Cow,Dog) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:50-200,ELISA=1:5000-10000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 57 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞核 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TRIM35: 9-100/492 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
TRIM35 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1, a B-box type 2 and a coiled-coil region. TRIM35 may play a role as a tumor suppressor and is implicated in the cell death mechanism. There are two named isoforms. Function: May play a role as a tumor suppressor. Implicated in the cell death mechanism (By similarity). Subcellular Location: Cytoplasm. Nucleus. Found predominantly in cytoplasm with a granular distribution. Found in punctuate nuclear bodies. Similarity: Belongs to the TRIM/RBCC family. Contains 1 B box-type zinc finger. Contains 1 B30.2/SPRY domain. Contains 1 RING-type zinc finger. SWISS: Q9UPQ4 Gene ID: 23087 Database links: Entrez Gene: 23087 Human Entrez Gene: 66854 Mouse SwissProt: Q9UPQ4 Human SwissProt: Q8C006 Mouse Unigene: 104223 Human Unigene: 43871 Mouse Unigene: 153980 Rat |
