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Centrin-1+Centrin-2 Rabbit pAb (bs-13848R)  
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產(chǎn)品編號 bs-13848R
英文名稱 Centrin-1+Centrin-2 Rabbit pAb
中文名稱 中心體蛋白1+2抗體
別    名 Caltractin; Caltractin isoform 2; CEN 1; CEN1; Centrin EF hand protein 1; Centrin-1; Centrin1; CETN 1; CETN; CETN1; CETN1_HUMAN; EF hand protein 1; 20kD calcium binding protein; CALT; caltractin; Caltractin isoform 1; CEN2; centrin; centrin, EF hand protein, 2; Centrin-2; Centrin2; CETN2; CETN2_HUMAN; EF hand protein 2; EF-hand protein.  
研究領(lǐng)域 細(xì)胞生物  信號轉(zhuǎn)導(dǎo)  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Mouse,Rat (predicted: Human,Cow)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 20 kDa
檢測分子量
細(xì)胞定位 細(xì)胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Centrin 1: 101-172/172 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項(xiàng) This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene plays important roles in the determination of centrosome position and segregation, and in the process of microtubule severing. This encoded protein is localized to the centrosome of interphase cells, and redistributes to the region of the spindle poles during mitosis, reflecting the dynamic behavior of the centrosome during the cell cycle. [provided by RefSeq, Jul 2008]

Function:
Plays a fundamental role in microtubule-organizing center structure and function.

Subcellular Location:
Cytoplasm, cytoskeleton, centrosome. Centrosome of interphase and mitotic cells.

Similarity:
Belongs to the centrin family.
Contains 4 EF-hand domains.

SWISS:
Q12798

Gene ID:
1068

Database links:

Entrez Gene: 1068 Human

Entrez Gene: 512850 Cow

Omim: 603187 Human

SwissProt: Q32LE3 Cow

SwissProt: Q12798 Human

Unigene: 122511 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (rat testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Centrin-1+Centrin-2) Polyclonal Antibody, Unconjugated (bs-13848R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
Paraformaldehyde-fixed, paraffin embedded (mouse testis); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (Centrin-1+Centrin-2) Polyclonal Antibody, Unconjugated (bs-13848R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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