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ITPKB Rabbit pAb (bs-17185R)  
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產(chǎn)品編號 bs-17185R
英文名稱 ITPKB Rabbit pAb
中文名稱 三磷酸肌醇3激酶B抗體
別    名 1D myo inositol trisphosphate 3 kinase B; 4; 5-trisphosphate 3-kinase B; Inositol 1 4 5 trisphosphate 3 kinase B; Inositol 1; Inositol trisphosphate 3 kinase B; Inositol-trisphosphate 3-kinase B; InsP 3-kinase B; IP3 3 kinase; IP3 3 kinase B; IP3 3-kinase B; IP3K; IP3K B; IP3KB; IP3KB_HUMAN; Itpkb.  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Rat (predicted: Human,Mouse,Sheep,Cow,Chicken,Dog,Horse)
產(chǎn)品應(yīng)用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 102 kDa
檢測分子量
細胞定位 細胞核 細胞漿 細胞膜 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ITPKB: 601-700/946 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity. [provided by RefSeq, Jul 2008]

Subunit:
Interacts with DMTN.

Similarity:
Belongs to the inositol phosphokinase (IPK) family.

SWISS:
P27987

Gene ID:
3707

Database links:

Entrez Gene: 3707 Human

Entrez Gene: 320404 Mouse

Entrez Gene: 54260 Rat

Omim: 147522 Human

SwissProt: P27987 Human

SwissProt: P42335 Rat

Unigene: 659396 Human

Unigene: 726323 Human

Unigene: 132535 Mouse

Unigene: 22498 Rat



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (Rat brain); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (ITPKB) Polyclonal Antibody, Unconjugated (bs-17185R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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