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SFRS3 Rabbit pAb (bs-17299R)  
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產(chǎn)品編號 bs-17299R
英文名稱 SFRS3 Rabbit pAb
中文名稱 絲氨酸/蘇氨酸SRp20抗體
別    名 arginine/serine-rich 3; Pre mRNA splicing factor SRP20; Pre-mRNA-splicing factor SRP20; Serine/arginine-rich splicing factor 3; Splicing factor; Splicing factor arginine/serine rich 20 kD; Splicing factor arginine/serine rich 3; SRp20; SRSF3; SRSF3_HUMAN; X16.  
研究領域 細胞生物  信號轉導  激酶和磷酸酶  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Mouse (predicted: Human,Rat,Rabbit,Sheep,Cow,Zebrafish,Chicken,Dog,Horse)
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 19 kDa
檢測分子量
細胞定位 細胞核 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SFRS3: 51-150/164 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants, one protein-coding and the other non-coding, have been found for this gene. [provided by RefSeq, Sep 2010]

Function:
May be involved in RNA processing in relation with cellular proliferation and/or maturation.

Subcellular Location:
Nucleus.

Post-translational modifications:
Extensively phosphorylated on serine residues in the RS domain.

Similarity:
Belongs to the splicing factor SR family.
Contains 1 RRM (RNA recognition motif) domain.

SWISS:
P84103

Gene ID:
6428

Database links:

Entrez Gene: 6428 Human

Entrez Gene: 282070 Cow

Entrez Gene: 20383 Mouse

Entrez Gene: 361814 Rat

Entrez Gene: 368925 Zebrafish

Omim: 603364 Human

SwissProt: P84103 Human

SwissProt: P84104 Mouse

SwissProt: Q9D6W4 Mouse

SwissProt: Q801U3 Zebrafish

Unigene: 405144 Human

Unigene: 6787 Mouse

Unigene: 3509 Zebrafish



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (mouse colon); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Incubation with (SFRS3) Polyclonal Antibody, Unconjugated (bs-17299R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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