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PPEF1 Rabbit pAb (bs-21055R)  
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產(chǎn)品編號 bs-21055R
英文名稱 PPEF1 Rabbit pAb
中文名稱 PPEF1蛋白抗體
別    名 PP 7; PP7; PPE1_HUMAN; PPEF 1; PPEF; PPEF-1; Ppef1; PPP 7C; PPP7C; PPP7CA; Protein phosphatase 7, catalytic subunit, alpha isozyme; Protein phosphatase EF hand calcium binding domain 1; Protein phosphatase serine/threonine type with EF hands; Protein phosphatase with EF calcium binding domain; Protein phosphatase with EF calcium-binding domain; Protein phosphatase with EF hand calcium binding domain 1; Serine/threonine protein phosphatase 7; Serine/threonine protein phosphatase with EF hands 1; Serine/threonine-protein phosphatase 7; Serine/threonine-protein phosphatase with EF-hands 1.  
研究領域 細胞生物  神經(jīng)生物學  信號轉導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應 Human
產(chǎn)品應用 IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 75 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PPEF1: 301-400/653 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes a member of the serine/threonine protein phosphatase with EF-hand motif family. The protein contains a protein phosphatase catalytic domain, and at least two EF-hand calcium-binding motifs in its C terminus. Although its substrate(s) is unknown, the encoded protein has been suggested to play a role in specific sensory neuron function and/or development. This gene shares high sequence similarity with the Drosophila retinal degeneration C (rdgC) gene. Several alternatively spliced transcript variants, each encoding a distinct isoform, have been described. [provided by RefSeq, Jul 2008]

Function:
May have a role in the recovery or adaptation response of photoreceptors. May have a role in development.

Tissue Specificity:
Detected in retina and retinal derived Y-79 retinoblastoma cells. Also found in fetal brain.

Similarity:
Belongs to the PPP phosphatase family.
Contains 3 EF-hand domains.
Contains 1 IQ domain.

SWISS:
O14829

Gene ID:
5475

Database links:

Entrez Gene: 5475 Human

Omim: 300109 Human

SwissProt: O14829 Human

Unigene: 211589 Human



產(chǎn)品圖片
Paraformaldehyde-fixed, paraffin embedded (human brain glioma); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (PPEF1) Polyclonal Antibody, Unconjugated (bs-21055R) at 1:400 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.
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