| 產(chǎn)品編號(hào) | D10315 |
| 英文名稱 | Zymosan A |
| 中文名稱 | 酵母聚糖A(進(jìn)口) |
| 別 名 | Zymosan A from Saccharomyces cerevisiae; Zymosans; Zymosan [immunological]; Zymosan [immunological reagent]; 酵母聚糖; 酵母多聚糖A; 酵母聚糖A（來(lái)源于釀酒酵母） |
| 克 隆 號(hào) | |
| CAS | 58856-93-2 |
| 理論分子量 | kDa |
| 檢測(cè)分子量 | |
| 保存條件 | Store at -20℃. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
CAS：58856-93-2 MDL：MFCD00082157 外觀： 米白色至淺棕色的有小團(tuán)塊的粉末 用途：用于誘導(dǎo)炎癥反應(yīng)。 Zymosan A from Saccharomyces cerevisiae has been used: ? as a positive control to determine the activation of complement cascade ? for respiratory burst (RB) assay ? to assess its effects on performance, immunity, heat shock protein and apoptosis related gene expressions of dairy cows under heat stress (HS) ? a stimulating agent in Krebs-Ringer phosphate (KRP) medium ? to induce thermal hyperalgesia in mice Biochem/physiol Actions Zymosan is prepared from yeast cell wall and consists of protein-carbohydrate complexes. It is used to induce experimental sterile inflammation. In macrophages, zymosan-induced responses include the induction of proinflammatory cytokines, arachidonate mobilization, protein phosphorylation, and inositol phosphate formation. Zymosan A also raises cyclin D2 levels suggesting a role for the latter in macrophage activation besides proliferation. It potentiates acute liver damage after galactosamine injection suggesting that certain types of nonparenchymal cells other than Kupffer cells are involved in zymosan action. Zymosan A, a 13 beta glucan contributes to the development of organic dust-induced respiratory disease. |
