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human CD35/PE (bsm-30114M-PE)  
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產品編號 bsm-30114M-PE
英文名稱 human CD35/PE
中文名稱 PE標記人CD35單克隆抗體
別    名 C3 binding protein; C3b/C4b receptor; C3BR; C4BR; CD 35; CD35; CD35 antigen; complement component (3b/4b) receptor 1 (Knops blood group); complement component (3b/4b) receptor 1 including Knops blood group system; Complement component receptor 1; Complement receptor 1; Complement receptor type 1; CR 1; CR1; CR1_HUMAN; KN; Knops blood group antigen.  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 8E4
交叉反應
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 274kDa
檢測分子量 160, 190, 220, and 250
性    狀 Liquid
亞    型 Mouse IgG1, k
純化方法 Affinity purified by Protein G
緩 沖 液 0.01M PBS, 0.5%BSA, 0.03% Proclin300
保存條件 Store at 2-8℃. Protect from light. Avoid freezing.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 This gene is a member of the receptors of complement activation (RCA) family and is located in the 'cluster RCA' region of chromosome 1. The genome is polymorphic at this locus with allele-specific splice variants encoding different isoforms, based on the presence/absence of long homologous repeats (LHRs). The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, and splenic follicular dendritic cells. The Knops blood group system is a system of antigens located on this protein. The protein mediates cellular binding to particles and immune complexes that have activated complement. Decreases in expression of this protein and/or mutations in this gene have been associated with gallbladder carcinomas, mesangiocapillary glomerulonephritis, systemic lupus erythematosus, sarcoidosis and Alzheimer's disease. Mutations in this gene have also been associated with a reduction in Plasmodium falciparum rosetting, conferring protection against severe malaria. [provided by RefSeq, May 2020]

SWISS:
P17927

Gene ID:
1378

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