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Maspin Mouse mAb (bsm-33895M)  
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50ul/1180.00元
100ul/1980.00元
大包裝/詢價
產(chǎn)品編號 bsm-33895M
英文名稱 Maspin Mouse mAb
中文名稱 抑癌基因單克隆抗體
別    名 mammary serine proteinase inhibitor; Maspin; Ovalbumin; PI-5; PI5; Protease inhibitor 5; Serine(or cysteine) peptidase inhibitor, clade B, member 5; Serpin B5; serpin peptidase inhibitor; Serpin peptidase inhibitor, clade B(ovalbumin), member 5; SERPINB5; SPB5_HUMAN; Spi5; Spi7  
抗體來源 Mouse
克隆類型 Monoclonal
克 隆 號 2F6
交叉反應 Human
產(chǎn)品應用 WB=1:500-1000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 42 kDa
檢測分子量
細胞定位 細胞漿 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human Maspin Protein. 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 PBS pH7.4, containing 0.02% Proclin300 as Preservative and 50% Glycerol.
保存條件 Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 The Maspin protein is a sour depressant of nenzyme of a kind of silk ammonia that represses the tumor, is the sour depressant of protei nenzyme one member within super household of the silk ammonia, it is in repress the tumor growth and transfer exertive certain function.

Function:
Tumor suppressor. It blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Subunit:
Interacts with IRF6.

Subcellular Location:
Secreted, extracellular space.

Tissue Specificity:
Normal mammary epithelial cells.

Similarity:
Belongs to the serpin family. Ov-serpin subfamily.

SWISS:
P36952

Gene ID:
5268

Database links:

Entrez Gene: 5268 Human

Entrez Gene: 20724 Mouse

Entrez Gene: 116589 Rat

Omim: 154790 Human

SwissProt: P36952 Human

SwissProt: P70124 Mouse

SwissProt: P70564 Rat

Unigene: 55279 Human

Unigene: 268618 Mouse

Unigene: 25752 Rat



Maspin蛋白是一種抑制腫瘤的絲氨酸蛋白酶抑制劑, 是絲氨酸蛋白酶抑制劑超家族中的一員,它在抑制腫瘤生長和轉(zhuǎn)移中發(fā)揮一定作用。
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