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CCL7 Rabbit pAb (bs-42364R)  
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產(chǎn)品編號 bs-42364R
英文名稱 CCL7 Rabbit pAb
中文名稱 單核細胞趨化蛋白3抗體
別    名 CCL7; C-C motif chemokine 7; Ccl7; CCL7_HUMAN; Chemokine CC motif ligand 7; FIC; MARC; MCP-3; Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; NC28; RP23-350G1.4; SCYA6; SCYA7; Small-inducible cytokine A7.  
抗體來源 Rabbit
克隆類型 Polyclonal
克 隆 號
交叉反應(yīng) Human
產(chǎn)品應(yīng)用 WB=1:500-2000
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 11 kDa
檢測分子量
細胞定位 分泌型蛋白 
濃    度 1mg/ml
免 疫 原 Recombinant human CCL7 protein 
亞    型
純化方法 affinity purified by Protein A
保存條件 Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹 This gene encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q. [provided by RefSeq, Jul 2008]

Function:
Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.

Subunit:
Monomer.

Subcellular Location:
Secreted.

Post-translational modifications:
O-glycosylated.

Similarity:
Belongs to the intercrine beta (chemokine CC) family.

SWISS:
P80098

Gene ID:
6354

Database links:

Entrez Gene : 6354 Human

Entrez Gene : 287561 Rat

Omim : 158106 Human

SwissProt : P80098 Human

SwissProt : Q9QXY8 Rat

Unigene : 251526 Human

Unigene : 26815 Rat



產(chǎn)品圖片
25 ug total protein per lane of various lysates (see on figure) probed with CCL7 polyclonal antibody, unconjugated (bs-42364R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
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