| 產(chǎn)品編號 | bsm-63149R |
| 英文名稱 | Adiponectin receptor protein 1 Recombinant Rabbit mAb |
| 中文名稱 | 脂聯(lián)素受體1重組兔單抗 |
| 別 名 | Adiponectin receptor protein 1; Progestin and adipoQ receptor family member I ; CGI-45; PAQR1; ADIPOR1. |
| 抗體來源 | Rabbit |
| 克隆類型 | Recombinant |
| 克 隆 號 | 2H4 |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:1000-1:2000,IHC-P=1:100-1:200,IHC-F=1:100-1:200,IF=1:50-1:200,Flow-Cyt=1:20-1:100,ICC/IF=1:50-1:200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 43 kDa |
| 檢測分子量 | 43 |
| 性 狀 | Liquid |
| 免 疫 原 | A synthesized peptide derived from human Adiponectin receptor protein 1: 1-46 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol. |
| 保存條件 | Store at 4℃ for short term. Store at -20℃ for long term. Avoid repeated freeze/thaw cycles. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Receptor for ADIPOQ, an essential hormone secreted by adipocytes that regulates glucose and lipid metabolism.Required for normal glucose and fat homeostasis and for maintaining a normal body weight. ADIPOQ-binding activates a signaling cascade that leads to increased AMPK activity, and ultimately to increased fatty acid oxidation, increased glucose uptake and decreased gluconeogenesis. Has high affinity for globular adiponectin and low affinity for full-length adiponectin. SWISS: Q96A54 Gene ID: 51094 脂聯(lián)素與受體結(jié)合后具有增強胰島素敏感性，抗高血糖，抗動脈粥樣硬化等生物學(xué)效應(yīng)，任何增加或減少脂聯(lián)素及其受體表達的方法都影響這些疾病的發(fā)生和發(fā)展. 脂聯(lián)素受體-1(AdipoR1和AdipoR2)同屬于PAQR家族，具有七次跨膜蛋白的特有結(jié)構(gòu)， mol wt:41kDa |
