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Carbonic Anhydrase I Recombinant Rabbit mAb (bsm-54409R)  
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產品編號 bsm-54409R
英文名稱 Carbonic Anhydrase I Recombinant Rabbit mAb
中文名稱 碳酸酐酶1重組兔單抗
別    名 Carbonic Anhydrase-I; Carbonic Anhydrase 1; Carbonic anhydrase1; Carbonic anhydrase-1; JW0122; CA 1; CA1; CA I; CA-1; CAI; CAN; Car 1; Car1; Carbonate dehydratase I; Carbonic anhydrase 1; Carbonic anhydrase B; Carbonic dehydratase; ECK0125; yadF; CAH1_HUMAN.  
研究領域 心血管  細胞生物  免疫學  信號轉導  
抗體來源 Rabbit
克隆類型 Recombinant
克 隆 號 2H4
交叉反應 Mouse,Rat (predicted: Human)
產品應用 WB=1:500-2000,IHC-P=1:100-500,IHC-F=1:50-200,IF=1:100-500
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 29 kDa
檢測分子量
細胞定位 細胞膜 分泌型蛋白 
性    狀 Liquid
濃    度 1mg/ml
免 疫 原 Recombinant human Carbonic Anhydrase I: 1-200/261 
亞    型 IgG
純化方法 affinity purified by Protein A
緩 沖 液 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
保存條件 Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antib
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產品介紹 Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA1 is closely linked to CA2 and CA3 genes on chromosome 8, and it encodes a cytosolic protein which is found at the highest level in erythrocytes. Variants of this gene have been described in some populations. Multiple alternatively spliced variants, encoding the same protein, have been identified. Transcript variants of CA1 utilizing alternative polyA_sites have been described in literature. [provided by RefSeq, Sep 2009]

Function:
Reversible hydration of carbon dioxide.

Subcellular Location:
Cytoplasm.

Similarity:
Belongs to the alpha-carbonic anhydrase family.

SWISS:
P00915

Gene ID:
759

Database links:

Entrez Gene: 759 Human

Entrez Gene: 12346 Mouse

Entrez Gene: 310218 Rat

Omim: 114800 Human

SwissProt: P00915 Human

SwissProt: P13634 Mouse

SwissProt: B0BNN3 Rat

Unigene: 23118 Human

Unigene: 273195 Mouse

Unigene: 6854 Rat



產品圖片
Sample: Lane 1: Large intestine (Mouse) Lysate at 40 ug Lane 2: Lung (Mouse) Lysate at 40 ug Lane 3: Stomach (Mouse) Lysate at 40 ug Lane 4: Bone (Mouse) Lysate at 40 ug Lane 5: Spleen (Mouse) Lysate at 40 ug Lane 6: Small intestine (Mouse) Lysate at 40 ug Lane 7: Lung (Mouse) Lysate at 40 ug Lane 8: Cerebrum (Mouse) Lysate at 40 ug Lane 9: Large intestine (Rat) Lysate at 40 ug Lane 10: Lung (Rat) Lysate at 40 ug Lane 11: Stomach (Rat) Lysate at 40 ug Lane 12: Bone (Rat) Lysate at 40 ug Lane 5: Spleen (Rat) Lysate at 40 ug Primary: Anti-Carbonic Anhydrase I (bsm-54409R) at 1/1000 dilution Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution Predicted band size: 30 kD Observed band size: 27 kD
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