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Anti-human PDCD1 / PD-1 / CD279 (Pembrolizumab Biosimilar) (BIO0058SM)  
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產(chǎn)品編號 BIO0058SM
英文名稱 Anti-human PDCD1 / PD-1 / CD279 (Pembrolizumab Biosimilar)
中文名稱
抗體來源
克隆類型 Monoclonal
克 隆 號
交叉反應(yīng) Human,Cynomolgus,Rhesus
產(chǎn)品應(yīng)用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
理論分子量 143.44 kDa
檢測分子量
性    狀 Lyophilized
亞    型 Human IgG4SP
純化方法 Protein A
保存條件 For long term storage, the produce should be stored at -20°C or lower.
注意事項 This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed PubMed
產(chǎn)品介紹
產(chǎn)品圖片
Pembrolizumab inhibited the tumor growth of MC38 on human PD-1 mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 44.0% at 0.18 mpk at D37.
Immobilized human PD-1 His at 2 ug/mL can bind Anti-PDCD1 / PD-1 / CD279 Reference Antibody (pembrolizumab), EC50=0.0039 ug/mL.
The purity of Anti-PDCD1 / PD-1 / CD279 Reference Antibody (pembrolizumab) is more than 95%, determined by SEC-HPLC.
Anti-PDCD1 / PD-1 / CD279 Reference Antibody (pembrolizumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.
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