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產(chǎn)品編號	BIO0404SM
英文名稱	Anti-human TNFRSF5 / CD40 (Selicrelumab Biosimilar)
中文名稱
抗體來源
克隆類型	Monoclonal
克隆號
交叉反應	Human
產(chǎn)品應用	not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.
理論分子量	146.2 kDa
檢測分子量
性狀	Lyophilized
亞型	Human IgG2SA
純化方法	Protein A
保存條件	For long term storage, the produce should be stored at -20°C or lower.
注意事項	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
PubMed	PubMed
產(chǎn)品介紹
產(chǎn)品圖片	Compared with the negative control group, selicrelumab had a significant increase in serum ALT content at a dose of 20 mpk, and a trend of increase in serum ALT at a dose of 1 mpk, but there was no statistica Selicrelumab inhibited the tumor growth of MC38 on Humanized CD40 mice. The result showed significant anti-tumor effects. Immobilized human CD40 His at 2 ug/mL can bind Anti-TNFRSF5 / CD40 Reference Antibody (selicrelumab), EC50=0.009782 ug/mL. The purity of Anti-TNFRSF5 / CD40 Reference Antibody (selicrelumab) is more than 95%, determined by SEC-HPLC. Anti-TNFRSF5 / CD40 Reference Antibody (selicrelumab) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 95%.