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Rabbit Anti-FASTK/BF488 Conjugated antibody (bs-1765R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-1765R-BF488
英文名稱 Rabbit Anti-FASTK/BF488 Conjugated antibody
中文名稱 BF488標記的Fas活化的絲/蘇氨酸激酶抗體
別    名 FASTK; Fas-activated serine/threonine kinase; Fas activated serine threonine kinase; Fas activated serine threonine kinase isoform 1; Fas activated serine threonine kinase isoform 4; FAST; FAST kinase; FLJ13079.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  細胞凋亡  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FAST kinase
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase was shown to be activated rapidly during Fas mediated apoptosis in Jurkat cells. In response to Fas receptor ligation, it phosphorylates TIA1, an apoptosis promoting nuclear RNA binding protein. The encoded protein is a strong inducer of lymphocyte apoptosis. Two transcript variants encoding different isoforms have been found for this gene. Other variants exist, but their full length natures have not yet been determined.

Subunit:
Interacts with TIA-1 and TIAR.

Tissue Specificity:
Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Similarity:
Belongs to the FAST protein kinase family.
Contains 1 RAP domain.

Database links:

Entrez Gene: 10922 Human

Entrez Gene: 66587 Mouse

Entrez Gene: 296741 Rat

Omim: 606965 Human

SwissProt: Q14296 Human

SwissProt: Q9JIX9 Mouse

Unigene: 647094 Human

Unigene: 28123 Mous



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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