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Rabbit Anti-MMP15/Gold Conjugated antibody (bs-1855R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1855R-Gold
英文名稱 Rabbit Anti-MMP15/Gold Conjugated antibody
中文名稱 膠體金標記的基質(zhì)金屬蛋白酶-15抗體
別    名 Matrix metalloproteinase-15; MMP 15; MMP-15; MMP15; Matrix metallopeptidase 15 membrane inserted; Matrix metalloproteinase 15 ; Membrane type 2 Matrix Metalloproteinase; Membrane type matrix metalloproteinase 2; MT MMP 2; MT2 MMP; MT2MMP; MTMMP 2; MTMMP2; SMCP 2; SMCP2; MMP15_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 腫瘤  免疫學  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, )
產(chǎn)品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61/76kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MMP15
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產(chǎn)品介紹 background:
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. [provided by RefSeq, Jul 2008].

Function:
Endopeptidase that degrades various components of the extracellular matrix. May activate progelatinase A.

Subcellular Location:
Membrane; Single-pass type I membrane protein; Extracellular side.

Tissue Specificity:
Appeared to be synthesized preferentially in liver, placenta, testis, colon and intestine. Substantial amounts are also detected in pancreas, kidney, lung, heart and skeletal muscle.

Post-translational modifications:
The precursor is cleaved by a furin endopeptidase (By similarity).

Similarity:
Belongs to the peptidase M10A family.
Contains 4 hemopexin-like domains.

Database links:

Entrez Gene: 4324 Human

Entrez Gene: 17388 Mouse

Omim: 602261 Human

SwissProt: P51511 Human

SwissProt: O54732 Mouse

Unigene: 80343 Human

Unigene: 217116 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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