| 產(chǎn)品編號 | bs-3904R-Gold |
| 英文名稱 | Rabbit Anti-HSD11B1/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的羥基類固醇脫氫酶11β1抗體 |
| 別 名 | 11 beta HSD 1; 11 beta HSD1; 11 beta hydroxysteroid dehydrogenase 1; 11 DH; 11DH; Corticosteroid 11 beta dehydrogenase isozyme 1; HDL; HSD 11; HSD11; HSD11B; HSD11L; Hydroxysteroid (11 beta) dehydrogenase 1; Hydroxysteroid (11 beta) dehydrogenase; MGC13539. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 細(xì)胞生物 免疫學(xué) 轉(zhuǎn)錄調(diào)節(jié)因子 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human, Mouse, Rat, Horse, (predicted: Dog, Pig, Cow, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 32kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human HSD11B1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: HSD11B1 is a microsomal enzyme that catalyses the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyse the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. Subunit: Homodimer. Subcellular Location: Endoplasmic reticulum membrane; Single-pass type II membrane protein. Tissue Specificity: Widely expressed. Highest expression in liver. Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family. Database links: Entrez Gene: 3290 Human Entrez Gene: 15483 Mouse Omim: 600713 Human SwissProt: Q6R0J2 Hamster SwissProt: P28845 Human SwissProt: P50172 Mouse SwissProt: Q7M3I4 Rabbit Unigene: 195040 Human Unigene: 28328 Mouse Unigene: 185798 Rat Unigene: 888 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
