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Rabbit Anti-TPRKB/PE-Cy7 Conjugated antibody (bs-17175R-PE-Cy7)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-17175R-PE-Cy7
英文名稱 Rabbit Anti-TPRKB/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的p53相關蛋白激酶結(jié)合蛋白抗體
別    名 CGI 121; My019; PRPK (p53 related protein kinase) binding protein; PRPK-binding protein; TP53RK binding protein; TP53RK-binding protein; Tprkb; TPRKB_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉(zhuǎn)導  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Rabbit, )
產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human TPRKB
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 Function:
Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. TPRKB acts as an allosteric effector that regulates the t(6)A activity of the complex. TPRKB is not required for tRNA modification (By similarity).

Subunit:
Component of the EKC/KEOPS complex composed of at least TP53RK, TPRKB, OSGEP and LAGE3; the whole complex dimerizes. Interacts with TP53RK/PRPK.

Subcellular Location:
Cytoplasm. Nucleus.

Tissue Specificity:
Widely expressed.

Similarity:
Belongs to the CGI121/TPRKB family.

Database links:

Entrez Gene: 425906 Chicken

Entrez Gene: 519224 Cow

Entrez Gene: 475794 Dog

Entrez Gene: 51002 Human

Entrez Gene: 69786 Mouse

Entrez Gene: 297411 Rat

Omim: 608680 Human

SwissProt: Q9Y3C4 Human

SwissProt: Q8QZZ7 Mouse

SwissProt: Q5PQR8 Rat

Unigene: 157401 Human

Unigene: 218434 Mouse

Unigene: 203015 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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